New Step by Step Map For ceesdekker
New Step by Step Map For ceesdekker
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Nanotechnology provides A variety of chances to lead to biology. In this article I'll existing illustrations where nanofabrication – the ability to make confined structures with dimensions at will – is employed to examine the biophysics of solitary molecules and cells. I will current some examples from our lab:
Our group research bacterial cell division which is aiming to represent a ‘base up biology’ in synthetic cells that will autonomously divide. Our primary interest lies in mobile division, chromatin construction, and spatial Manage.
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Nanofabrication of electrodes with sub-5 nm spacing for transport experiments on one molecules and steel clusters
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever layout in 2005. (nl)
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic constructions to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental purpose of spatial confinement at the molecular and mobile stage. Our initiatives include things like the next:
Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim with the pore is highlighted in crimson, and also a 3D rendering in the movement in the DNA rod is exhibited.
‘Indeed, I understand men and women were stunned at some time. At the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t study much any more. The sector went more into the application aspect, how you could integrate nanotubes into electronic circuits.
Dekker started https://www.ceesdekker.net out his research on solitary carbon nanotubes in 1993 when he create a new line of investigate to review electrical transportation by way of single natural and organic molecules amongst nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was reached inside a collaboration While using the team of Nobel laureate Richard Smalley. STM and nanolithography strategies were being accustomed to reveal that these nanotubes are quantum wires at The only-molecule amount, with exceptional Actual physical Homes.
Since 2000 he moved to one-molecule biophysics and nanobiology, with analysis from studies of DNA loop extrusion and supercoiling to DNA translocation by nanopores. A lot more recently his investigation has focused on finding out chromatin structure and cell division with microbes on chip, even though he is also aiming to in the end Establish synthetic cells from The underside up.
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It was an incredibly interesting time, in the course of which I been given a lot of help from Delft College of Technological know-how, in which I used to be a professor at enough time, And that i started numerous collaborations with molecular biologists. That aided me master a great deal.’